At Assured Pharmaceutical, we offer our patients complete peace of mind with regard to their health.

Search

In Stock

Keytruda Pembrolizumab

Brand Name : Keytruda
Composition : Pembrolizumab
Manufactured by : Merck Pharmaceuticals Ltd.
Strength : 100 mg
Form : Injection
Packing : Pack of 1 Vial

265,000.00

Compare

buy keytruda online | buy pembrolizumab | keytruda buy hong kong

Pembrolizumab, sold under the brand name Keytruda, is a humanized antibody used in cancer immunotherapy that treats melanoma, lung cancer, head and neck cancer, Hodgkin lymphoma, and stomach cancer. It is given by slow injection into a vein.

Common side effects include fatigue, musculoskeletal pain, decreased appetite, itchy skin (pruritus), diarrhea, nausea, rash, fever (pyrexia), cough, difficulty breathing (dyspnea), constipation, pain, and abdominal pain. It is an IgG4 isotype antibody that blocks a protective mechanism of cancer cells and thereby, allows the immune system to destroy them. It targets the programmed cell death protein 1 (PD-1) receptor of lymphocytes. It works by targeting the cellular pathway of proteins found on the body’s immune cells and some cancer cells, known as PD-1/PD-L1.

Pembrolizumab was approved for medical use in the United States in 2014. In 2017, the US Food and Drug Administration (FDA) approved it for any unresectable or metastatic solid tumor with certain genetic anomalies (mismatch repair deficiency or microsatellite instability). It is on the World Health Organization’s List of Essential Medicines

Medical uses

220px PD L1 positive lung adenocarcinoma intermed mag

Micrograph showing a PD-L1 positive non-small cell lung carcinoma. PD-L1 immunostain

As of 2019, pembrolizumab is used via intravenous infusion to treat inoperable or metastatic melanoma, metastatic non-small cell lung cancer (NSCLC) in certain situations, as a first-line treatment for metastatic bladder cancer in patients who can’t receive cisplatin-based chemotherapy and have high levels of PD-L1, as a second-line treatment for head and neck squamous cell carcinoma (HNSCC), after platinum-based chemotherapy, for the treatment of adult and pediatric patients with refractory classic Hodgkin’s lymphoma (cHL), and recurrent locally advanced or metastatic esophageal squamous cell carcinoma.

buy keytruda online | buy pembrolizumab | keytruda buy hong kong

For NSCLC, pembrolizumab is a first-line treatment if the cancer overexpresses PD-L1, a PD-1 receptor ligand, and the cancer has no mutations in EGFR or in ALK; if chemotherapy has already been administered, then pembrolizumab can be used as a second-line treatment, but if the cancer has EGFR or ALK mutations, agents targeting those mutations should be used first.[3][16] Assessment of PD-L1 expression must be conducted with a validated and approved companion diagnostic.

220px Pembrolizumab results as in Lung cancer keynote studies KEYNOTE 024 KEYNOTE 042 KEYNOTE 189 KEYNOTE 407

Pembrolizumab (Pembro) use for treatment of Lung cancer in the first line with or without chemotherapy (Chemo). Median overall survival in months (M). Hazarad Ration (HR). KEYNOTE-024, KEYNOTE-042, KEYNOTE-189, and KEYNOTE-407. Adapted from: First line Immunotherapy for Non-Small Cell Lung Cancer Nasser NJ, Gorenberg M, Agbarya A. Pharmaceuticals (Basel). 2020 Nov 8;13(11):373. https://doi.org/10.3390/ph13110373

In 2017, the U.S. Food and Drug Administration (FDA) approved pembrolizumab for any unresectable or metastatic solid tumor with certain genetic anomalies (mismatch repair deficiency or microsatellite instability). This was the first time the FDA approved a cancer drug based on tumor genetics rather than tissue type or tumor site; therefore, pembrolizumab is a so-called tissue-agnostic drug.

In the European Union, pembrolizumab is indicated for:

buy keytruda online | buy pembrolizumab | keytruda buy hong kong

  • the treatment of advanced (unresectable or metastatic) melanoma in adults as monotherapy.
  • the adjuvant treatment of adults with Stage III melanoma and lymph node involvement who have undergone complete resection as monotherapy.
  • the first-line treatment of metastatic non-small cell lung carcinoma (NSCLC) in adults whose tumours express PD-L1 with a ≥ 50% tumour proportion score (TPS) with no EGFR or ALK positive tumour mutations as monotherapy.
  • the first-line treatment of metastatic non-squamous NSCLC in adults whose tumours have no EGFR or ALK positive mutations in combination with pemetrexed and platinum chemotherapy.
  • the first-line treatment of metastatic squamous NSCLC in adults in combination with carboplatin and either paclitaxel or nab-paclitaxel.
  • the treatment of locally advanced or metastatic NSCLC in adults whose tumours express PD-L1 with a ≥ 1% TPS and who have received at least one prior chemotherapy regimen. People with EGFR or ALK positive tumour mutations should also have received targeted therapy before receiving Keytruda as monotherapy.
  • the treatment of adults with relapsed or refractory classical Hodgkin lymphoma (cHL) who have failed autologous stem cell transplant (ASCT) and brentuximab vedotin (BV), or who are transplant-ineligible and have failed BV as monotherapy.
  • the treatment of locally advanced or metastatic urothelial carcinoma in adults who have received prior platinum-containing chemotherapy as monotherapy..
  • the treatment of locally advanced or metastatic urothelial carcinoma in adults who are not eligible for cisplatin-containing chemotherapy and whose tumours express PD L1 with a combined positive score (CPS) ≥ 10 as monotherapy.
  • the first-line treatment of metastatic or unresectable recurrent head and neck squamous cell carcinoma (HNSCC) in adults whose tumours express PD-L1 with a CPS ≥ 1 as monotherapy or in combination with platinum and 5-fluorouracil (5-FU) chemotherapy.
  • the treatment of recurrent or metastatic HNSCC in adults whose tumours express PD-L1 with a ≥ 50% TPS and progressing on or after platinum-containing chemotherapy as monotherapy.
  • the first-line treatment of advanced renal cell carcinoma (RCC) in adults in combination with axitinib.

buy keytruda online | buy pembrolizumab | keytruda buy hong kong

Bestsellers

Categories:
Compare
PK-0008

FENTANYL PILLS

230.002,400.00
Fentanyl Pills In the mid-1990s, fentanyl was introduced for palliative use with the fentanyl patch, followed in the next decade by the introduction of the fentanyl lollipop, dissolving tablets, and sublingual spray which are resorbed through the skin inside the mouth.As of 2012 fentanyl w
Categories:
Compare

Humalog KwikPen

32,636.0095,050.00
What's in box?
  • Each Pack contains 5pens
  • 3ml per pen
  • 100units per Ml
  • 15ml per pack
  • 1500units per pack
Categories:
Compare
PK-0019

OXYCODONE 30 MG PILLS

270.001,500.00
Oxycodone 30mg pills may be habit forming. Never share this medicine with another person, especially someone with a history of drug abuse or addiction. Keep the medication in a place where others cannot get to it. Selling or giving away oxycodone to any other person is against the law. Roxicodone 30 mg Pills Generic Name: oxycodone (OX-i-KOE-done) Brand Name: Examples include OxyIR and Roxicodone Roxicodone is used for: Treating moderate to severe pain.
Categories:
Compare

UltiCare 0.5 ml Insulin Syringe Short Needle 30g, 5/16 Inch (Pack Count 100)

2,172.00
WEIGHT 0.93 lbs GAUGE 30g ML/CC 0.5 ml NEEDLE LENGTH 5/16 Inch (8mm) PACK COUNT 100 SOURCE Store, Warehouse
Categories:
Compare
PP-0002

ECSTASY PILLS

150.001,200.00
Ecstasy Pills, MDMA Pills Powder Crystals was initially popular in the nightclub scene and at all-night dance parties (“raves”), but the drug now affects a broader range of people who more commonly call the drug Ecstasy or Molly. How do people use MDMA Powder Crystals
Categories:
Compare
PK-0030

XANAX ALPRAZOLAM PILLS

170.00843.00
XANAX ALPRAZOLAM PILLS may be habit-forming. Misuse of habit-forming medicine can cause addiction, overdose, or death. Do not drink alcohol while taking Xanax. This medication can increase the effects of alcohol. Alprazolam may be habit-forming and should be used only by the person for whom it was prescribed.
Categories:
Compare
PK-0009

Hydrocodone

150.001,040.00
Hydrocodone produces varying degrees of euphoria based upon dosage and the tolerance of the person. is now one of the most common recreational prescription drugs in America, along with Oxycodone . Recreational hydrocodone use is particularly prevalent among teenagers and young adults because of the drug’s widespread availability.

Back to Top