At Assured Pharmaceutical, we offer our patients complete peace of mind with regard to their health.


(buy lantus solostar | where to buy lantus solostar | buy lantus solostar uk)

Insulin glargine, marketed under the names Lantus among others, is a long-acting insulin, used in the management of type I and type II diabetes. It is typically the recommended long acting insulin in the United Kingdom. It is used once a day as an injection just under the skin. Effects generally begin an hour after use.

Common side effects include low blood sugar, problems at the site of injection, itchiness, and weight gain. Other serious side effects include low blood potassium. NPH insulin rather than insulin glargine is generally preferred in pregnancy. After injection microcrystals slowly release insulin for about 24 hours. This insulin causes body tissues to absorb glucose from the blood and decreases glucose production by the liver.

Insulin glargine was approved for medical use in the United States in 2000. In 2018, it was the 26th most commonly prescribed medication in the United States with more than 24 million prescriptions

Medical uses

(buy lantus solostar | where to buy lantus solostar | buy lantus solostar uk)

The long-acting insulin class, which includes insulin glargine, do not appear much better than neutral protamine Hagedorn (NPH) insulin, but do have a greater cost, making them, as of 2010, not cost effective for the treatment of type 2 diabetes. It is unclear if there is a difference in hypoglycemia, given the significance of dose, and not enough data to determine any differences with respect to long term outcomes. It is not typically the recommended long acting insulin in the United Kingdom.

Mixing with other insulins

Unlike some other longer-acting insulins, glargine must not be diluted or mixed with other insulin or solution in the same syringe. However, this restriction has been questioned.

Adverse effects

Common side effects include low blood sugar, problems at the site of injection, itchiness, and weight gain. Serious side effects include low blood potassium.

As of 2012, tentative evidence shows no association between insulin glargine and cancer. Previous studies had raised concerns.


Mechanism of action

(buy lantus solostar | where to buy lantus solostar | buy lantus solostar uk)

Insulin glargine differs from human insulin by replacing asparagine with glycine in position 21 of the A-chain and by carboxy-terminal extension of B-chain by 2 arginine residues. The arginine amino acids shift the isoelectric point from a pH of 5.4 to 6.7, making the molecule more soluble at an acidic pH and less soluble at physiological pH. The isoelectric shift also allows for the subcutaneous injection of a clear solution. The glycine substitution prevents deamidation of the acid-sensitive asparagine at acidic pH. In the neutral subcutaneous space, higher-order aggregates form, resulting in a slow, peakless dissolution and absorption of insulin from the site of injection. It can achieve a peakless level for at least 24 hours.

Acceptance and repartition in the body

Insulin glargine is formulated at an acidic pH 4, where it is completely water-soluble. After subcutaneous injection of the acidic solute (which can cause discomfort and a stinging sensation), when a physiologic pH (approximately 7.4) is achieved the increase in pH causes the insulin to come out of solution resulting in the formation of higher order aggregates of insulin hexamers. The higher order aggregation slows the dissociation of the hexamers into insulin monomers, the functional and physiologically active unit of insulin. This gradual process ensures that small amounts of insulin glargine are released into the body continuously, giving an almost peakless profile.




Roxicodone 5 mg Pills Generic Name: oxycodone (OX-i-KOE-done) Brand Name: Examples include OxyIR and Roxicodone Roxicodone is used for: Treating moderate to severe pain. It may be used before surgery to sedate the patient and reduce fear. It may also be used for other conditions as determi

Buy Byetta online

Es stehen zwei vorgefüllte Stifte zur Abgabe von Einzeldosen von 5 µg oder 10 µg zur Verfügung. Jeder Fertigpen gibt 60 Dosen ab, um eine 30-tägige zweimal tägliche Verabreichung (BID) zu ermöglichen. BYETTA wird als sterile Lösung zur subkutanen Injektion mit 250 µg/ml Exenatid in den folgenden Packungen geliefert: 5 µg pro Dosis, 60 Dosen, 1,2 ml Fertigpen  10 µg pro Dosis, 60 Dosen, 2,4 ml Fertigpen.

Dilaudid 2mg

Dilaudid 2mg, Hydromorphone can slow or stop your breathing, and may be habit-forming. Use only your prescribed dose, and swallow an extended-release pill whole to avoid a potentially fatal dose. Never share Dilaudid 2mg with another person

BD Insulin Syringe with Ultra-Fine Needle 31g, 0.3cc, 15/64 inch (6mm)- Box of 100

WEIGHT 1 lbs DIMENSIONS 7 × 6 × 4 in GAUGE 31g ML/CC 0.3 ml NEEDLE LENGTH 15/64 inch (6mm) PACK COUNT 100 SOURCE Green, Store, Warehouse


Morphine 60 mg Pills irritation that can make pain worse. Narcotic pain relievers, such as morphine and codeine , are the most powerful pain treatments. These usually are reserved for the most intense pain. They can cause serious side effects, can be addictive and often cause constipation


What's in the box:
  • A box which comes with 1,2 or 3 pens.
  • Each pen comes in either 0.5mg/ml or 1mg/ml.


Nembutal Liquid Since it was so easy to overdose on Nembutal (whether accidentally or intentionally), it was almost universally taken off the market and replaced by safer sleeping pills. Nembutal was removed from the Australian prescribing schedule in 1998. However, Nembutal remains in use by veterin

Back to Top