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Ozempic

What’s in the box:

  • A box which comes with 1,2 or 3 pens.
  • Each pen comes in either 0.5mg/ml or 1mg/ml.

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Buy Ozempic Online, Semaglutide, sold under the brand name Ozempic, is an anti-diabetic medication used to treat type 2 diabetes and chronic weight management.

Semaglutide acts like human glucagon-like peptide-1 (GLP-1) such that it increases insulin secretion, thereby increasing sugar metabolism. Ozempic is distributed as a metered subcutaneous injection in a prefilled pen or oral form. One of its advantages over other anti-diabetic drugs is its long duration of action. Thus, only a once-a-week injection is sufficient.

An injection version (Ozempic) was approved for medical use in the United States in December 2017 and the European Union, Canada, and Japan in 2018. A performance taken by mouth (Rybelsus) was approved for medical use in the United States in September 2019 and the European Union in April 2020. It is the first glucagon-like peptide receptor protein treatment approved for use in the United States that does not need to be injected. Novo Nordisk developed it.

Side effects including nausea, vomiting, diarrhea, abdominal pain, and constipation may occur.

On 4 June 2021, the US FDA approved semaglutide injection sold under the brand name Wegovy for chronic weight management in adults.

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Medical uses

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Semaglutide is prepared for subcutaneous injection and is available in prefilled pen. It is recommended for once-weekly injection.

Adverse effects

See also the Warning section.

Bulge/redness/itching at the injection area, fatigue, nausea, vomiting, diarrhea may occur. Nauseousness usually lowers as you continue to use Ozempic. Notify your physician or pharmacist promptly if any of these consequences last or get more threatening.

Recall that your doctor has prescribed this medicine because they have thought that your benefit is more significant than the risk of side effects. Numerous individuals using this medicine do not have severe side effects.

Speak to the doctor right away if you have any severe side effects, including signs of kidney problems, vision changes (such as decreased/blurred vision). Ozempic for sale | Ozempic for sale | 

Semaglutide has rarely caused a very severe disease of the pancreas (pancreatitis). Get medical assistance straight away if you develop signs of pancreatitis, including severe belly/abdominal discomfort, vomiting that doesn’t stop.

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Although semaglutide by itself usually does not cause low blood sugar (hypoglycemia). Low blood sugar may occur if prescribed with other diabetes medications. Talk with your doctor or pharmacist about whether the dose(s) of your other diabetes medication(s) needs to be lowered. Drinking large quantities of alcohol, not getting enough calories from food, or doing cumbersome exercise may also lead to low blood sugar. Symptoms may include sudden sweating, shaking, fast heartbeat, hunger, blurred vision, dizziness, headache, or tingling hands/feet. It is a good habit to carry glucose tablets or gel to treat low blood sugar. Check with your doctor or pharmacist to find out what you should do if you miss a meal.

Symptoms of high blood sugar (hyperglycemia) include increased thirst/urination. If these symptoms occur, tell your doctor right away. Your dosage may need to be improved.

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A severe allergic reaction to this drug is rare. Nonetheless, you should get medical assistance straight away if you notice any signs of a severe allergic reaction. Including rash, itching, and swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.

This is not a complete list of possible side effects. Contact your doctor or pharmacist if you notice other effects not listed above.

In the US – Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.

In Canada – Call your doctor for medical advice about side effects. You may report side effects to Health Canada at 1-866-234-2345.

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Keep in the refrigerator. After first use, keep this medicine in the fridge or at room temperature, away from warmness and sunlight. Discard 8 weeks after first use. Keep all medications away from children and pets.

Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Confer your druggist or local garbage removal organization.

Keep this medication away from children or pets.

Before opening:
Store in the refrigerator between 2°C – 8°C
Do not freeze
Keep away from cooling element
Recommended to store in the butter compartment
During use:
During use, Ozempic pen can be kept for 8 weeks in the refrigerator between 2-8°C or at a temperature below 30°C
Do not freeze.
Keep the pen cap on to protect from direct light when not in use.

Do not use this medicine if it appears colorless or transparent.

Do not dispose of medication in trash or down wastewater. Speak to your pharmacist about properly disposing of medication not in use to protect the environment.

Medication interactions

Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.

Beta-blocker medicines (such as metoprolol, propranolol, glaucoma eye drops such as timolol). May prevent the fast/pounding heartbeat you would usually feel when your blood sugar falls too low (hypoglycemia). Other symptoms of low blood sugar, such as dizziness, hunger, or sweating, are not affected by these drugs.

Many drugs can affect your blood sugar, making it harder to control. Before starting, stopping, or changing any medication:

  1. Talk with your doctor or pharmacist about how the medication may affect your blood sugar.
  2. Check your blood sugar regularly as directed and share the results with your doctor.
  3. Tell your doctor right away if you have high or low blood sugar symptoms. Your doctor may need to adjust your diabetes medication, exercise program, or diet.

How Does Ozempic Work For Weight Loss?

Ozempic helps you lose weight by acting on the part of your brain responsible for food reward systems and cravings. The drug also works on your stomach to decrease gastric emptying, making you feel fuller faster and longer. These effects are all driven by Ozempic’s stimulation of the GLP-1 receptor, a primary regulator of appetite and calorie intake.

Mechanism of action

Semaglutide is a glucagon-like peptide-1 receptor agonist. It increases the production of insulin, a hormone that lowers the blood sugar level. It also appears to enhance the growth of β cells in the pancreas, which are the sites of insulin production. On the other hand, it inhibits glucagon, which increases blood sugar. It additionally reduces food intake by lowering appetite and slowing down digestion in the stomach. In this way, it works in body fat reduction.

Structure

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Semaglutide is chemically similar to human glucagon-like peptide-1 (GLP-1), with 94% similarity. The only differences are two amino acid substitutions at positions 8 and 34, where alanine and lysine are replaced by 2-aminoisobutyric acid and arginine, respectively. Amino acid substitution at position 8 prevents chemical breakdown by an enzyme dipeptidyl peptidase-4. Acylation with a spacer and C-18 fatty diacid chain increases the drug binding to blood protein (albumin), enabling a more prolonged presence in the blood circulation. Its half-life in the blood is about 7 days (165–184 hours). Therefore, a once-weekly injection is enough.

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What's in box?
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